Fri Jul 08 2022

119 articles - From Friday Jul 01 2022 to Friday Jul 08 2022

parm_toc.knit

Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…

Clin Gastroenterol Hepatol

AGA Clinical Practice Update on New Technology and Innovation for Surveillance and Screening in Barrett's Esophagus: Expert Review.

Methods The Best Practice Advice statements presented here were developed from expert review of existing literature combined with discussion and expert opinion to provide practical advice. Formal rating of the quality of evidence or strength of BPAs was not the intent of this clinical practice update.

Pubmed   Journal   ReadQx 

Gastroenterology

CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease.

This multidisciplinary collaboration involving patients and clinical experts has produced the first COS that can be applied to RCTs of CD and UC.

Pubmed   Journal   ReadQx 

Gut

British Society of Gastroenterology guidelines on the management of functional dyspepsia.

These provide both the strength of the recommendations and the overall quality of evidence. Finally, in this guideline, we consider novel treatments that are in development, as well as highlighting areas of unmet need and priorities for future research.

Pubmed   Journal   ReadQx 


Meta-analysis

meta-analyses and systematic reviews

Aliment Pharmacol Ther

Living in the non-alcoholic fatty liver disease silent epidemic: a qualitative systematic review of patients' perspectives.

This review synthesises first-hand accounts of individuals with NAFLD. With the growing burden of NAFLD, future public interventions must consider individual views for success to be found. The identified themes serve as a forefront for consideration for public policies. Ultimately, NAFLD is a multisystem disease, which must be managed by a multidisciplinary team.

Pubmed   Journal   ReadQx 

Endoscopy

Long-Term Outcomes of Per-Oral Endoscopic Myotomy (POEM) for Achalasia: a Systematic Review and Meta-analysis.

Long-term clinical efficacy of POEM persists in nearly 87% of patients with achalasia. Post-POEM symptomatic reflux seems to remain stable over time. Risk for Barrett's esophagus and peptic strictures appears minimal.

Pubmed   Journal   ReadQx 

Gastroenterology

Liver Stiffness on Magnetic Resonance Elastography and the MEFIB Index and Liver-Related Outcomes in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Individual Participants.

Liver stiffness assessed by MRE is associated with liver-related events and the combination of MRE and FIB-4 has excellent negative predictive value for hepatic decompensation. These data have important implications for clinical practice.

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis

Alterations in the Course of Inflammatory Bowel Disease Following Liver Transplantation: A Systematic Review and Meta-analysis.

We conclude that IBD activity remains unchanged (or improved/unchanged) in most IBD patients following LT. Furthermore, IBD type, age, and follow-up length can influence the IBD course after LT.

Pubmed   Journal   ReadQx 

J Crohns Colitis

Psychiatric disorders in adult and paediatric patients with inflammatory bowel diseases - a systematic review and meta-analysis.

The prevalence of psychiatric comorbidities was high (11- 82%) in patients with IBD and was higher than in the background population. Addressing mental health problems in patients with IBD can improve their adherence to treatment and the somatic disease course and, consequently, reduce morbidity and mortality.

Pubmed   Journal   ReadQx 


Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

Classic drugs in the time of new drugs: Real-world, long-term outcomes of thiopurine monotherapy in 1016 patients with inflammatory bowel disease.

In real-world practice, thiopurine monotherapy remains an effective, safe and durable treatment option for patients with CD or UC, including in the era of biologics.

Pubmed   Journal   ReadQx 

Impact of Rome IV Irritable Bowel Syndrome on Work and Activities of Daily Living.

Patients with IBS experience a substantial impact on their work and activities of daily living because of their IBS. Future studies should assess the impact of medical interventions on the ability to work and participate in social activities.

Pubmed   Journal   ReadQx 

Impact of thiopurines and tumour necrosis factor antagonists on primary sclerosing cholangitis outcomes in patients with inflammatory bowel disease.

Patients with PSC and IBD who are exposed to thiopurines or anti-TNF agents are not at excess risk of biliary tract cancer or liver transplantation.

Pubmed   Journal   ReadQx 

Risk of dementia in patients with inflammatory bowel disease: a Danish population-based study.

UC and CD are associated with slightly increased all-cause dementia risk, particularly frontotemporal dementia in CD patients. Frequent healthcare system contacts by patients with IBD and detection bias may play a role in the association.

Pubmed   Journal   ReadQx 

Treatment patterns of anti-tumour necrosis factor-alpha and prognosis of paediatric and adult-onset inflammatory bowel disease in Korea: a nationwide population-based study.

These data demonstrate that the prevalence of IBD has increased over time, especially among paediatric patients. Given the magnitude of paediatric IBD disease burden, a multi-faceted approach is needed for early detection and vigilant monitoring to aim for better prognosis.

Pubmed   Journal   ReadQx 

Gastroenterology

Acetyl-coA Synthetase 2 potentiates macropinocytosis and muscle wasting through metabolic reprogramming in pancreatic cancer.

ACSS2-mediated metabolic reprogramming activates ZIP4 pathway, and promotes macropinocytosis via SDC1/DNM2 and drives muscle wasting through GSK3ß/TRAIL axis, which potentially provides additional nutrients for macropinocytosis in pancreatic cancer.

Pubmed   Journal   ReadQx 

Association of Proton Pump Inhibitor Use With All-cause and Cause-specific Mortality.

After accounting for protopathic bias, PPI use was not associated with higher risks of all-cause mortality and mortality due to major causes.

Pubmed   Journal   ReadQx 

Integrated analysis of colorectal cancer reveals cross-cohort gut microbial signatures and associated serum metabolites.

We generated cross-cohort metagenomic signatures of CRC, some of which linked to in-house CRC-associated serum metabolites. The microbial and metabolic shifts may have wide population relevance.

Pubmed   Journal   ReadQx 

Malondialdehyde-acetaldehyde extracellular matrix protein adducts attenuate unfolded protein response during alcohol and smoking-induced pancreatitis.

The combined alcohol and smoking generate stable MAA-ECM adducts that increase ER stress and acinar cell death due to attenuated UPR and suppress the expression of cell cycle regulators. Targeting aldehyde-adducts might provide a novel therapeutic strategy for the management of RAP and CP.

Pubmed   Journal   ReadQx 

Population-level metagenomics uncovers distinct effects of multiple medications on the human gut microbiome.

Our large-scale metagenomics unravels extensive and disruptive impacts of individual and multiple drug exposures on the human gut microbiome, providing a drug-microbe catalog as a basis for a deeper understanding of the role of the microbiome in drug efficacy and toxicity.

Pubmed   Journal   ReadQx 

Radiomics-Based Machine Learning Models Can Detect Pancreatic Cancer on Prediagnostic CTs at a Substantial Lead Time Prior to Clinical Diagnosis.

Radiomics-based ML models can detect PDAC from normal pancreas when it is beyond human interrogation capability at a substantial lead time prior to clinical diagnosis. Prospective validation and integration of such models with complementary fluid-based biomarkers has the potential for PDAC detection at a stage when surgical cure is a possibility.

Pubmed   Journal   ReadQx 

Gastrointest Endosc

Improving 30-day mortality following percutaneous endoscopic gastrostomy tube placement in England from 2007 to 2019: a retrospective national cohort analysis of 87,862 patients.

30 day mortality following PEG insertion has fallen 60% over 13 years. Dementia or stroke as a PEG indication fell and the time interval from stroke to PEG insertion increased. These findings may be attributable to improved patient selection and timing for PEG insertion.

Pubmed   Journal   ReadQx 

Tip-in Endoscopic Mucosal Resection as an Alternative to Endoscopic Submucosal Dissection for 20-30-mm Non-Pedunculated Colorectal Neoplasms.

Tip-in EMR is comparable to ESD with respect to the local recurrence rate but has a shorter procedure time, despite the lower en bloc and R0 resection rate for 20-30-mm non-pedunculated colorectal neoplasms without fold convergence or non-lifting sign. Thus, Tip-in EMR could be a feasible alternative to ESD in these lesions.

Pubmed   Journal   ReadQx 

Gut

Autoimmune gastritis: long-term natural history in naïve Helicobacter pylori-negative patients.

Objective Autoimmune gastritis (AIG) is an immunomediated disease targeting parietal cells, eventually resulting in oxyntic-restricted atrophy. This long-term follow-up study aimed at elucidating the natural history, histological phenotype(s), and associated cancer risk of patients with AIG consistently tested comorbidity.

Pubmed   Journal   ReadQx 

Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.

Genotyping was performed using the InfiniumGlobal Screening Array (V.24v2, Illumina) and the OmniExpress Array (V.24v1-0a, Illumina). Results Associations with variants rs738409 in as a novel protective factor for HCC in patients with alcohol-related cirrhosis.

Pubmed   Journal   ReadQx 

Hepatology

Age and the relative importance of liver-related deaths in nonalcoholic fatty liver disease.

The relative importance of liver-related death increases with age in NAFLD patients, especially among women. In patients with cirrhosis, liver disease is the leading cause of death.

Pubmed   Journal   ReadQx 

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver.

Hepatic endothelial ALK1 signaling protects from development of vascular malformations preserving organ-specific endothelial differentiation and angiocrine signaling. The long-term surviving Alk1 HEC-KO HHT model offers novel opportunities to develop targeted therapies for this severe disease.

Pubmed   Journal   ReadQx 

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease.

Our data uncover the importance of a lipid membrane composition rich in DHA and its lipid autacoid derivatives to have optimal hepatic mitochondrial and metabolic efficiency.

Pubmed   Journal   ReadQx 

Mafld and excessive alcohol consumption are both independent risk factors for mortality.

MAFLD increases mortality risk independent of excessive alcohol consumption. This underscores the importance of MAFLD, even in patients with excessive alcohol consumption.

Pubmed   Journal   ReadQx 

RNA helicase DEAD-box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling.

These findings provide new mechanistic insight into the role of DDX5 in mTORC1 regulation and NASH progression, as well as suggest a number of new targets and a promising lead compound for therapeutic interventions against NASH.

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis

Clostridium difficile Infection in Patients with Ulcerative Colitis Treated with Tofacitinib in the Ulcerative Colitis Program.

CDIs among patients with UC receiving tofacitinib were infrequent, cases were mild-moderate in severity, and most resolved with treatment.

Pubmed   Journal   ReadQx 

Indirect Costs of Inflammatory Bowel Diseases: A Comparison of Patient-Reported Outcomes Across 12 European Countries.

The study showed a high relevance of the indirect cost of IBD in the context of economic evaluation, as well as a between-country variability of work-related impairment or informal care.

Pubmed   Journal   ReadQx 

Primary Care Professionals' Attitudes Towards Vaccination Recommendation for Patients With Inflammatory Bowel Disease.

There is room for improvement of vaccination recommendations by PCPs. Promoting continuing education and use of clinical tools may help support PCP immunization practices for patients with IBD.

Pubmed   Journal   ReadQx 

The Risk of Serious Infections Before and After Anti-TNF Therapy in Inflammatory Bowel Disease: A Retrospective Cohort Study.

In routine clinical practice in Sweden, the incidence rate of serious infection among IBD patients did not increase with anti-TNF therapy. Instead, serious infections seemed to decrease more than 1 year after initiation of anti-TNF treatment.

Pubmed   Journal   ReadQx 

Trends in Medical Management of Moderately to Severely Active Ulcerative Colitis: A Nationwide Retrospective Analysis.

As biologic drugs have become increasingly available for UC management, they have increasingly been used at earlier stages of disease management. Large-scale analyses of prescribing behaviors provide evidence supporting early use of biologics compared with step-up therapy and use of thiopurine and biologic combination therapy.

Pubmed   Journal   ReadQx 

J Crohns Colitis

Biological therapy for budesonide-refractory, -dependent or -intolerant microscopic colitis: a multicentre cohort study from the GETAID.

This is the first multicentre cohort study showing that half of patients treated with anti-TNF therapy for MC achieved clinical remission in case of budesonide failure.

Pubmed   Journal   ReadQx 

Hereditary Colorectal Cancer Syndromes and Inflammatory Bowel Diseases: an ECCO CONFER Multicenter Case Series.

To date, this is the largest case series of patients with IBD and HCCS. The most frequent diagnosis of HCCS associated with IBD was Lynch syndrome. These data demonstrate the high malignancy rate and surgical intervention rate in this IBD cohort, despite the endoscopic surveillance. The optimal medical approach still needs to be addressed.

Pubmed   Journal   ReadQx 

Hypoxia-Inducible Factor 1-Alpha Stabilizers in the Treatment of Inflammatory Bowel Diseases: Oxygen as a Novel IBD Therapy?

In line with these criteria, hypoxia-inducible factor (HIF)-1a stabilizers, acting via inhibition of prolyl hydroxylase enzymes, are emerging as an innovative therapeutic strategy. We herein review the mechanism of action and available clinical data for HIF-1a stabilizers and its potential place in the future IBD treatment algorithm.

Pubmed   Journal   ReadQx 

Increased Risk of Non-Conventional and Invisible Dysplasias in Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

Nearly a third of PSC-IBD patients developed dysplasia, which is often associated with non-conventional dysplastic features, invisible endoscopic/gross appearance, right/proximal-sided colon, multifocality, and advanced neoplasia on follow-up. These findings underscore the importance of recognizing these non-conventional subtypes by practicing pathologists and the need for careful and frequent endoscopic surveillance with random biopsies in PSC-IBD patients.

Pubmed   Journal   ReadQx 

PU.1-driven Th9 cells promote colorectal cancer in experimental colitis models through IL-6 effects in intestinal epithelial cells.

IL-9 is a crucial regulator of tumor growth in colitis-associated neoplasias and emerges as potential target for therapy.

Pubmed   Journal   ReadQx 

Timing of live attenuated vaccination in infants exposed to infliximab or adalimumab in utero: A prospective cohort study in 107 children.

Almost one quarter of infants born to mothers receiving anti-TNF during pregnancy have detectable anti-TNF at 6 months. In order to limit the time to live-attenuattated vaccination in infants of mothers receiving anti-TNF during pregnancy, the results of a cord drug level at birth and a 2 nd sample =1 month thereafter can be used to estimate the time for full anti-TNF clearance in these children.

Pubmed   Journal   ReadQx 

J Hepatol

Digital pathology with artificial intelligence analyses provides greater insights into treatment-induced fibrosis regression in NASH.

Fibrosis regression following hepatic fat reduction occurs initially in the perisinusoidal regions, around areas of steatosis reduction. Digital pathology provides new insights in treatment-induced fibrosis regression in NASH, which are not captured by current staging systems.

Pubmed   Journal   ReadQx 

Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis.

Cholangitis is characterised by intrahepatic expansion and inflammatory maturation of type 2 conventional dendritic cells in response to biliary injury. Therefore, type 2 conventional dendritic cells and their inflammatory mediators might be potential therapeutic targets for the treatment of PSC.

Pubmed   Journal   ReadQx 

Liver stiffness measurement by vibration-controlled transient elastography improves outcome prediction in primary biliary cholangitis.

LSM by VCTE is a major, independent, validated predictor of PBC outcome. Its value as a surrogate endpoint for clinical benefit in PBC should be considered.

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

Saccharomyces boulardii and Lactulose for Childhood Functional Constipation: A Multicenter Randomized Controlled Trial.

Methods This open-label randomized controlled trial was conducted at 10 university hospitals in Korea. Children who were diagnosed with functional constipation were allocated to 3 groups (lactulose monotherapy, combination therapy, and monotherapy was not superior to lactulose monotherapy or combination therapy and showed a higher drug change rate, supporting the current recommendation of probiotics in the treatment of childhood functional constipation.

Pubmed   Journal   ReadQx 

A Potential Role of Cholinergic Dysfunction on Impaired Colon Motility in Experimental Intestinal Chagas Disease.

Background/aims Chagasic megacolon is caused by -induced damage of smooth muscles was accompanied by motility disorders such as decreased intestinal peristalsis and cholinergic system response impairment. This study allows integration of the natural history of Chagasic megacolon motility disorders and opens new perspectives for the design of effective therapeutic.

Pubmed   Journal   ReadQx 

Association Between Eating Behavior, Frequency of Meals, and Functional Dyspepsia in Young Japanese Population.

In the young Japanese people, the frequency of meals may be independently inversely associated with prevalence of FD. In particular, skipping breakfast and/or lunch was associated with the prevalence of FD.

Pubmed   Journal   ReadQx 

Association Between Gut Regulatory Hormones and Post-operative Weight Loss Following Gastrectomy in Patients With Gastric Cancer.

Significant weight reduction was common after subtotal gastrectomy for gastric cancer with a negative correlation pre-operative plasma ghrelin levels. Incretin hormones are modestly but significantly increased after subtotal gastrectomy; however, these changes did not affect the weight changes.

Pubmed   Journal   ReadQx 

Efficacy of Slow Nutrient Drinking Test for Evaluating Postprandial Distress Symptom in Japanese Patients With Functional Dyspepsia.

The 30-minute slow nutrient drinking test is a minimally invasive method of effectively evaluating symptoms of postprandial distress syndrome among patients with FD, in Japan.

Pubmed   Journal   ReadQx 

General Well-being and Coping Strategies in Adult Eosinophilic Esophagitis Patients.

EoE has a significant negative impact on mental HRQOL, with less effective coping strategies--specifically in males, being a relevant determinant. Thus, a pro-active approach towards coping mechanisms is needed in order to enhance HRQOL and manage patients' burden of EoE.

Pubmed   Journal   ReadQx 

Normal Values of High-resolution Anorectal Manometry of Healthy Indians.

The present study provides normal data for the Indian population that can be used for comparison and further work. Age, gender, and BMI affect anorectal parameters in HRAM and should be considered while reporting.

Pubmed   Journal   ReadQx 

Risk Factors for Self-reported Irritable Bowel Syndrome With Prior Psychiatric Disorder: The Lifelines Cohort Study.

Despite its limitations this study suggests that prior psychiatric disorder is an important risk factor in a quarter of IBS onsets. Negative health perception and multiple bodily symptoms are associated with al IBS onsets in line with the cognitive-behavior model of IBS. Prior psychiatric disorder may predict an optimal response to psychiatric treatment. Further studies could usefully study mechanisms linking IBS to prior psychiatric disorder.

Pubmed   Journal   ReadQx 

Safety and Efficacy of Elobixibat, an Ileal Bile Acid Transporter Inhibitor, in Elderly Patients With Chronic Idiopathic Constipation According to Administration Time: Interim Analysis of Post-marketing Surveillance.

The results suggested that elobixibat was well-tolerated and efficacious in elderly patients with chronic constipation and can be administered before any meals.

Pubmed   Journal   ReadQx 

The Predictive Value of Intraoperative Esophageal Functional Luminal Imaging Probe Panometry in Patients With Achalasia Undergoing Peroral Endoscopic Myotomy: A Single-center Experience.

While FLIP panometry was not significantly associated with the clinical course of achalasia, FLIP panometry was associated with POC following POEM and may complement manometry in the functional evaluation of esophageal motility disorders.

Pubmed   Journal   ReadQx 

The Upper Esophageal Sphincter Distensibility Index Measured Using Functional Lumen Imaging Probe Identifies Defective Barrier Function of the Upper Esophageal Sphincter.

A higher UES-DI measures defective barrier function which could may be the main pathophysiology that generates supra-esophageal symptoms.

Pubmed   Journal   ReadQx 


Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther

Review article: Exclude or expose? The paradox of conceptually opposite treatments for irritable bowel syndrome.

Even though exclusion diets and exposure-based CBT are conceptually opposite, they each have proven efficacy. Clinicians should familiarise themselves with both treatments. Further research is needed on predictors, mechanisms and moderators of treatment outcomes.

Pubmed   Journal   ReadQx 

Gastroenterology

High-quality Studies of Artificial Intelligence in Colonoscopy Illuminate a Next Important Step.

Pubmed   Journal   ReadQx 

Hundreds of Novel DNA Viruses From a Single Healthy Patient: Biomarker Potential for Colorectal Cancer.

Pubmed   Journal   ReadQx 

Inclusive Clinical Trials for Disorders of Gut-Brain Interactions.

Pubmed   Journal   ReadQx 

Navigating the Stormy Sea of Infected Necrotizing Pancreatitis: Are We There Yet? Well Almost!

Pubmed   Journal   ReadQx 

The Current Role of Vonoprazan in Helicobacter pylori Treatment.

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis

Should a Psychologist Be a Mandatory Component of Inflammatory Bowel Disease Consults? Yes.

Pubmed   Journal   ReadQx 

J Hepatol

Augmenter of liver regeneration: mitochondrial function and steatohepatitis.

Whereas high-fat diet-fed ALR-deficient mice develop nonalcoholic steatohepatitis (NASH) and fibrosis, hepatic and serum levels of ALR are lower than normal in human NASH and NASH-cirrhosis. Thus ALR deficiency may be a critical predisposing cause for the pathogenesis and progression of NASH.

Pubmed   Journal   ReadQx 

COVID-19 positive donor for solid organ transplantation.

As the evolving outbreak of SARS-CoV-2 continues, alongside the presence of vaccines and new treatment options, clinicians should consider transplanting organs from deceased donors with active SARS-CoV-2 infection to recipients with limited opportunities for transplantation and natural or vaccine induced specific immunity. This article seeks to describe an expert opinion for the use of organs from deceased donors with resolved or active SARS-CoV-2 infection in the absence of more definitive data and standardized acceptance patterns.

Pubmed   Journal   ReadQx 

Hydroxymethylbilane synthase (aka porphobilinogen deaminase): a novel metabolic tumor suppressor gene in hepatocellular carcinoma.

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

Eating Behavior in Functional Dyspepsia.

Pubmed   Journal   ReadQx 

How to Implement the 3-Phase FODMAP Diet Into Gastroenterological Practice.

While the diet has shown improved irritable bowel syndrome outcomes across studies, it is important to acknowledge the essential role of dietitians in implementing, tailoring, and managing the diet to achieve the best outcome for each individual.

Pubmed   Journal   ReadQx 

Irritable Bowel Syndrome or Psychiatric Disorders: Which Comes First?

Pubmed   Journal   ReadQx 

Role of Nutrient Drinking Test in Functional Dyspepsia.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies

Gut

Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers.

Pubmed   Journal   ReadQx 

Hepatology

IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcoholic hepatitis - more questions than answers !

Pubmed   Journal   ReadQx 

Letter to the Editor: Combination treatment with IL- 1 antagonist, pentoxifylline & zinc for severe alcoholic hepatitis: Are we there yet?

Pubmed   Journal   ReadQx 

Letter to the editor: L-ornithine L-aspartate in acute treatment of severe hepatic encephalopathy: A double-blind randomized controlled trial.

Pubmed   Journal   ReadQx 

Letter to the Editor: Some reflection on the research related to METTL1 promoting radiotherapy resistance in hepatocellular carcinoma.

Pubmed   Journal   ReadQx 

Reply by Authors.

Pubmed   Journal   ReadQx 

Response from Authors of HEP-21-2131.R1.

Pubmed   Journal   ReadQx 

Risk factors of NAFLD in preterm and low birthweight. More questions than answers!

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis

Should a Psychologist Be a Mandatory Component of IBD Consults? Yes-Authors' Reply.

Pubmed   Journal   ReadQx 

J Hepatol

Non-responders to sofosbuvir/velpatasvir/voxilaprevir in the treatment of chronic hepatitis C infection.

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

Comment to the Description of a Novel Cohesinopathy in Chronic Intestinal Pseudo Obstruction.

Pubmed   Journal   ReadQx 

Estimating the Self-reported Prevalence of Non-celiac Gluten Sensitivity in the Korean Population.

Pubmed   Journal   ReadQx 

Microbial Dysbiosis in Achalasia: Insights on How to Prevent Cancer.

Pubmed   Journal   ReadQx 

Non-celiac Gluten Sensitivity or Celiac Disease, This Is Still the Question.

Pubmed   Journal   ReadQx 


Others

all remaining publications eg case reports, images of the month, etc…

Am J Gastroenterol

Calendar of Courses, Symposiums and Conferences.

Pubmed   Journal   ReadQx 

Reviewer Recognition.

Pubmed   Journal   ReadQx 

Clin Gastroenterol Hepatol

How to Train the Next Generation to Provide High-Quality Peer-Reviews.

Pubmed   Journal   ReadQx 

Endoscopy

"Spider-traction" endoscopic submucosal dissection for a submucosal lesion invading the site of a previous appendectomy.

Pubmed   Journal   ReadQx 

A rare case of a windsock-shaped intraluminal duodenal diverticulum treated successfully with endoscopic diverticulectomy.

Pubmed   Journal   ReadQx 

A safe needle-knife precut papillotomy technique in a patient with a naïve papilla and surgically altered anatomy.

Pubmed   Journal   ReadQx 

A traction device to aid the intubation of a surgically altered bile duct during ERCP.

Pubmed   Journal   ReadQx 

Biliary stent placement with modified Shim technique in a child with tracheoesophageal fistula and esophageal stricture.

Pubmed   Journal   ReadQx 

Clip with rubber band modification for dynamic traction in colonic endoscopic submucosal dissection.

Pubmed   Journal   ReadQx 

Cold-snare endoscopic mucosal resection of large duodenal laterally spreading tumors: is cold the future gold standard?

Pubmed   Journal   ReadQx 

Combination of ERCP with endoscopic ultrasound-guided hepaticogastrostomy and hepaticoduodenostomy for biliary drainage in malignant hilar biliary obstruction.

Pubmed   Journal   ReadQx 

Double-balloon enteroscopy-assisted polypectomy for a solitary jejunal Peutz-Jeghers polyp causing anemia.

Pubmed   Journal   ReadQx 

Double-clip traction endoscopic submucosal dissection: an interesting alternative method for the resection of pedunculated polyps.

Pubmed   Journal   ReadQx 

Electrohydraulic lithotripsy using peroral cholangioscopy for impaction of stent-stone complex around biliary plastic stent.

Pubmed   Journal   ReadQx 

Endoscopic submucosal dissection for complete removal of a residual colorectal tumor involving a diverticulum.

Pubmed   Journal   ReadQx 

Endoscopic ultrasound-guided choledochoduodenostomy with pyloric occlusion by proximal flange of electrocautery-enhanced lumen-apposing metal stent: solving a rare adverse event.

Pubmed   Journal   ReadQx 

Fluoroscopic balloon dilatation with antegrade and retrograde endoscopes is useful for complete pharyngoesophageal obstruction after radiation therapy.

Pubmed   Journal   ReadQx 

How to reduce the ecological impact of gastric peroral endoscopic myotomy: a small effort for the environment.

Pubmed   Journal   ReadQx 

Malignant duodenocolic fistula successfully treated with self-expandable partially covered metal stent and endoscopic suturing.

Pubmed   Journal   ReadQx 

Reopenable-clip band-assisted underwater endoscopic mucosal resection to obtain a large specimen.

Pubmed   Journal   ReadQx 

Rescuing the impacted endoscopic suturing device during endoscopic sleeve gastroplasty.

Pubmed   Journal   ReadQx 

Successful resection of a 16-cm half-circumferential lesion at the greater curvature of the stomach using the endoscopic submucosal large-tunnel method.

Pubmed   Journal   ReadQx 

Underwater hybrid endoscopic mucosal resection: a valid option for selected lesions.

Pubmed   Journal   ReadQx 

Gastroenterology

An atypical cause of musculoskeletal pain in a patient with chronic inflammatory bowel disease.

Pubmed   Journal   ReadQx 

An Unusual Cause of Gastric Variceal Bleeding.

Pubmed   Journal   ReadQx 

Apsychia during colonoscopy.

Pubmed   Journal   ReadQx 

Diffuse gastrointestinal polyposis with skin, hair, and nail changes.

Pubmed   Journal   ReadQx 

Endoscopy COVID-19 Testing Requirements Disproportionately Affect Communities that are Medically Underserved and May Worsen Health Care Disparities.

Pubmed   Journal   ReadQx 

Hepatocellular carcinoma risk declines but remains high enough for screening in the first 7 years after HCV cure with DAAs in patients with cirrhosis or high FIB-4.

Pubmed   Journal   ReadQx 

Painless rectal bleeding in patient with prostate cancer.

Pubmed   Journal   ReadQx 

Penile necrosis in a patient with untreated Crohn's Disease.

Pubmed   Journal   ReadQx 

Gastrointest Endosc

Liver injury following the treatment of a duodenal varix with histoacryl glue.

Pubmed   Journal   ReadQx 

Gut

Cold versus hot EMR for large duodenal adenomas.

Pubmed   Journal   ReadQx 

Impact of pre-procedural testing on SARS-CoV-2 transmission to endoscopy staff.

Pubmed   Journal   ReadQx 

Refining genetic and molecular classifications to facilitate breakthrough treatments in intrahepatic cholangiocarcinoma: are we there yet?

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis

Tofacitinib for the Treatment of Pouch-Related Disorders: A Case Series.

Pubmed   Journal   ReadQx 

J Crohns Colitis

Phage Therapy Against Adherent-invasive E. coli: Towards a Promising Treatment of Crohn's Disease Patients?

Pubmed   Journal   ReadQx 

J Hepatol

In Memoriam: Wu Mengchao.

Pubmed   Journal   ReadQx